TCRD v6.12.4 Release Date: 20211029 ====================== This README describes changes from v6.11.0 ChEMBL ====== The ChEMBL activities in the cmpd_activity table have been replaced with all qualifying activities from chembl_29. The 'ChEMBL First Reference Year' and 'ChEMBL Selective Compound' rows in tdl_info have also been updated based on the new data from chembl_29. DrugCentral =========== All drug_activities in the drug_activity table have been replaced with the data from the latest version of DrugCentral (20211022). Rows in disease with dtype = 'DrugCentral Indication' have also been updated. JensenLab PubMed Scores ======================= JensenLab PubMed text-mining scores have been reloaded. This includes all rows in the pmscore table and the rows in tdl_info where itype = 'JensenLab PubMed Score'. TDLs ==== TDLs have been recalculated and updated. JensenLab DISEASES ================== The disease associations from DISEASES have been updated. Mondo and Mondo IDs in desease table ==================================== Created new tables mondo, mondo_parent and mondo_xref and these tables have been populated with the Mondo ontology. A new column (disease.mondoid) has been added and populated. DRGC Resources ============== The data in table drgc_resources has been replaced with the Pharos-ready resources available via the RSS API on 20211029. TIGA ==== The TIGA data in tables tiga and tiga_provenance has been replaced with the latest version (20210915).